Police are investigating a two-vehicle collision outside Newcastle today.

Shortly before 1pm (Wednesday 13 April 2016), emergency services were called to a head-on collision between a car and a truck on Tourle Street Bridge, Kooragang.

A 25-year-old female driver was treated at the scene by NSW Ambulance Paramedics before being taken to John Hunter Hospital in a serious condition.

The male driver of the truck was taken to John Hunter Hospital for mandatory testing.

Traffic and Highway Patrol with the assistance of Crime Scene investigators are currently attending and have commenced an investigation into the incident.

No further information is available at this stage.